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Deception through Mimicry: A Cellular Antiviral Strategy

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Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular… Click to show full abstract

Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.

Keywords: ebola virus; antiviral strategy; deception mimicry; cellular antiviral; mimicry cellular

Journal Title: Cell
Year Published: 2018

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