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Stars Are Not in Outer Space: Astrocytes Respond to Environmental Cues

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By in vivo screening in zebrafish larvae, Wheeler et al. identify environmental agents that directly modulate transcriptional programs of astrocytes. The herbicide linuron exploits the unfolded protein response pathway to induce a… Click to show full abstract

By in vivo screening in zebrafish larvae, Wheeler et al. identify environmental agents that directly modulate transcriptional programs of astrocytes. The herbicide linuron exploits the unfolded protein response pathway to induce a pro-inflammatory program in reactive astrocytes that potentiates inflammatory tissue damage in the CNS.

Keywords: environmental cues; astrocytes respond; stars outer; space astrocytes; respond environmental; outer space

Journal Title: Cell
Year Published: 2019

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