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In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021).… Click to show full abstract
In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021). These findings overturn the long-standing premise that osteoclasts differentiate solely from hematopoietic precursors and undergo apoptosis after completing resorption.
Keywords:
goes green;
bone resorption;
bone;
resorption goes;
resorption
Journal Title: Cell
Year Published: 2021
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Journal Title: Cell
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!