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Ancestry matters: Building inclusivity into preclinical study design

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Human cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable… Click to show full abstract

Human cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable and widely translatable. We lay out practical actions that can be taken to improve inclusivity in study design.

Keywords: inclusivity; ancestry matters; matters building; study design

Journal Title: Cell
Year Published: 2021

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