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Summary The Chematica program was used to autonomously design synthetic pathways to eight structurally diverse targets, including seven commercially valuable bioactive substances and one natural product. All of these computer-planned… Click to show full abstract
Summary The Chematica program was used to autonomously design synthetic pathways to eight structurally diverse targets, including seven commercially valuable bioactive substances and one natural product. All of these computer-planned routes were successfully executed in the laboratory and offer significant yield improvements and cost savings over previous approaches, provide alternatives to patented routes, or produce targets that were not synthesized previously.
Keywords:
diverse medicinally;
medicinally relevant;
efficient syntheses;
syntheses diverse;
executed laboratory;
computer
Journal Title: Chem
Year Published: 2018
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Journal Title: Chem
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!