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Accessing aliphatic alcohols for metallaphotoredox catalyzed C(sp3)-arylation

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Common cross-coupling reactions to obtain C(sp2)–C(sp3)-bonds are hampered by the abundance of nucleophilic and electrophilic functional groups. Recently in Nature, Dong and MacMillan developed a mild activation of a diverse… Click to show full abstract

Common cross-coupling reactions to obtain C(sp2)–C(sp3)-bonds are hampered by the abundance of nucleophilic and electrophilic functional groups. Recently in Nature, Dong and MacMillan developed a mild activation of a diverse range of alcohols with an N-heterocyclic carbene (NHC) salt and merged it with nickel photoredox dual catalytic arylation.

Keywords: aliphatic alcohols; catalyzed sp3; arylation; metallaphotoredox catalyzed; accessing aliphatic; alcohols metallaphotoredox

Journal Title: Chem
Year Published: 2021

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