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A week later, she was re-admitted with a syncopal episode. Her hemoglobin was 6.1 g/dL. Computed tomography (CT) showed retroperitoneal (RP) bleeding. She was transferred to our tertiary hospital and… Click to show full abstract
A week later, she was re-admitted with a syncopal episode. Her hemoglobin was 6.1 g/dL. Computed tomography (CT) showed retroperitoneal (RP) bleeding. She was transferred to our tertiary hospital and was found to be in shock. Blood work revealed prolonged activated prothrombin time and normal prothrombin time. She had not received heparin products in over 3 weeks. Mixing studies did not correct the defect, suggesting the presence of an inhibitor. Testing of factor VIII showed reduced activity at 8%. A Bethesda assay confirmed very high titers of factor VIII inhibitor (1:64).
Journal Title: Chest
Year Published: 2019
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