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Performance of the Xpert MTB/RIF Ultra Assay for Determining Cause of Death by TB in Tissue Samples Obtained by Minimally Invasive Autopsies

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An estimated 1.5 million deaths were attributable to TB in 2018. However, some uncertainty exists as to the exact global figures, given that approximately 30% of incident cases are not… Click to show full abstract

An estimated 1.5 million deaths were attributable to TB in 2018. However, some uncertainty exists as to the exact global figures, given that approximately 30% of incident cases are not diagnosed, and because of the difficulties of ascertaining TB as cause of death (CoD). Undoubtedly, complete diagnostic autopsies (CDAs) constitute the gold standard for establishing a diagnosis of TB at death. However, CDAs are seldom performed in high-TB-burden countries because of the scarcity of trained pathologists, the time-consuming nature of the

Keywords: death; performance xpert; cause death; mtb rif; xpert mtb

Journal Title: Chest
Year Published: 2020

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