LAUSR

Abstract Introduction About 25%–35% of polytraumatized patients have a profound alteration of hemostasis on arrival at the hospital (acute traumatic coagulopathy [CAT]). Viscoelastic tests (ROTEM®) measure the hemostatic capacity and provide an early detection of CAT. The objectives of this study are to describe the initial thromboelastogram of these patients and to determine the prevalence of CAT according to predefined thromboelastographic profiles. Methods Single-center, observational, prospective study in polytraumatic patients. Initial blood and thromboelastographic test (ROTEM®) were made, and pre-hospital, hospital, transfusion, initial surgical/angiographic interventions, cardiac arrest and mortality data were collected. ROTEM®-based, patients were classified as: normal, hypercoagulable, hypocoagulable, hypocoagulable+hyperfibrinolytic and isolated hyperfibrinolysis. Results One hundred and twenty-three patients were analyzed. 32 cases (26%) with CAT: 15 patients with hypocoagulability, 9 with hyperfibrinolysis alone and 8 with hypocoagulability+hyperfibrinolysis. The CAT group, related to the normal group, presented higher ISS (23 vs 16, P .01), higher blood products transfusion (2.5 vs 0; P = .001), more cardiac arrest (19 vs 1%, P .01), and higher mortality (34 vs 5%, P .01). The subgroup with hypocoagulability/hyperfibrinolysis, related to the groups with hypocoagulability or hyperfibrinolysis alone, presented a higher ISS (41 vs 25 vs 15, P .01), higher angiographic procedures (62% vs 13% vs 0%, P .01) and higher mortality (75% vs 33% vs 0%, P = .05). Conclusions Twenty-six percent of the polytrauma patients presented early coagulopathy assessed by thromboelastography. It is associated with higher consumption of blood products and lower survival. The presence of hypocoagulability+hyperfibrinolysis is associated with greater severity and a higher requirement of blood products.