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Oxaliplatin-induced Immune Thrombocytopenia: A Case Report and Literature Review.

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Abstract Oxaliplatin-induced immune thrombocytopenia is a rare manifestation of oxaliplatin hypersensitivity, presenting as an acute onset of severe thrombocytopenia after oxaliplatin administration. No standard therapeutic approach outside of permanent discontinuation… Click to show full abstract

Abstract Oxaliplatin-induced immune thrombocytopenia is a rare manifestation of oxaliplatin hypersensitivity, presenting as an acute onset of severe thrombocytopenia after oxaliplatin administration. No standard therapeutic approach outside of permanent discontinuation of oxaliplatin exists. Here, we present a case of oxaliplatin-induced immune thrombocytopenia occurring after oxaliplatin retreatment for metastatic colon cancer. Possible mechanisms of disease and approach to treatment are discussed.

Keywords: oxaliplatin induced; thrombocytopenia; case; induced immune; immune thrombocytopenia; oxaliplatin

Journal Title: Clinical colorectal cancer
Year Published: 2020

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