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Transplants for Acute Alcoholic Hepatitis: Controversies and Early Successes.

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Liver transplant for severe alcohol-associated hepatitis remains a controversial practice despite evidence for a substantial survival benefit compared with medical therapy and posttransplant alcohol relapse rates comparable with previously published… Click to show full abstract

Liver transplant for severe alcohol-associated hepatitis remains a controversial practice despite evidence for a substantial survival benefit compared with medical therapy and posttransplant alcohol relapse rates comparable with previously published studies in alcohol-associated cirrhosis. The controversy stems in part from concern regarding patient selection practices, lack of long-term follow-up data, and the potential negative public perception of the practice affecting organ donation. Despite these concerns, it seems that early liver transplant for alcohol-associated hepatitis is increasingly being offered to selected patients across the United States and the world.

Keywords: alcohol associated; hepatitis; transplants acute; hepatitis controversies; acute alcoholic; alcoholic hepatitis

Journal Title: Clinics in liver disease
Year Published: 2021

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