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A Rare Clinical Entity in Bladder Cancer: Paraneoplastic Cerebellar Degeneration

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Neurologic symptoms according to involvement of the central nervous system in bladder cancer is uncommon. Our knowledge about neurologic symptoms related to paraneoplastic syndrome in bladder cancer is limited. Bladder… Click to show full abstract

Neurologic symptoms according to involvement of the central nervous system in bladder cancer is uncommon. Our knowledge about neurologic symptoms related to paraneoplastic syndrome in bladder cancer is limited. Bladder cancer presenting with paraneoplastic cerebellar degeneration has been reported 4 times in the literature to date. Paraneoplastic neurological syndrome is a rarely seen clinical situation independent of tumor stage thought to develop linked to autoimmunity via antigens released from tumor cells. The most common antibody in paraneoplastic cerebellar degeneration is anti-Yo. For paraneoplastic neurological syndrome treatment the general opinion is for early tumor treatment. We present a 47-year-old male patient with antieYopositive paraneoplastic cerebellar degeneration associated with bladder cancer.

Keywords: cancer; bladder cancer; cerebellar degeneration; paraneoplastic cerebellar

Journal Title: Clinical Genitourinary Cancer
Year Published: 2017

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