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Sunitinib has demonstrated efficacy, notably in metastatic renal cell carcinoma, but has also induced frequent diverse adverse events and has a large panel of drug interaction, notably with CYP 450.… Click to show full abstract
Sunitinib has demonstrated efficacy, notably in metastatic renal cell carcinoma, but has also induced frequent diverse adverse events and has a large panel of drug interaction, notably with CYP 450. Sunitinib needs close monitoring for frail patients with high risk of side effects or drug interaction. We describe a successful therapeutic pharmacokinetic drug monitoring plan for a patient with a cardiac transplant presenting with metastatic renal cell carcinoma while adapting the dose of sunitinib.
Keywords:
drug;
interaction sunitinib;
drug monitoring;
drug interaction
Journal Title: Clinical Genitourinary Cancer
Year Published: 2017
Link to full text (if available)
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Journal Title: Clinical Genitourinary Cancer
Year Published: 2017
Link to full text (if available)
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recommendations!