Vitamin B12 (Cobalamin) deficiency is a well-known cause of central and peripheral nervous system dysfunction, including sensorimotor peripheral neuropathy [1]. In individuals with normal renal function, a normal or low… Click to show full abstract
Vitamin B12 (Cobalamin) deficiency is a well-known cause of central and peripheral nervous system dysfunction, including sensorimotor peripheral neuropathy [1]. In individuals with normal renal function, a normal or low serum B12 level, high plasma methylmalonic acid (MMA) and homocysteine (Hcy) levels indicates a functional B12 deficiency, where there is failure of intracellular transport of B12 by transcobalamin-2.
               
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