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Carrying on with liver transplantation during the COVID-19 emergency: Report from piedmont region

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Abstract Background The COVID-19 pandemic is an emergency worldwide. In Italy, Liver transplant activity was carried on, but despite all efforts, a 25% reduction of procured organs has already been… Click to show full abstract

Abstract Background The COVID-19 pandemic is an emergency worldwide. In Italy, Liver transplant activity was carried on, but despite all efforts, a 25% reduction of procured organs has already been observed during the first 4 weeks of the outbreak. Aims To analyze if our strategy and organization of LT pathway during the first two months of the COVID-19 emergency succeeded in keeping a high level of LT activity, comparing the number of LT in the first two months with the same period of time in 2019. Methods We compared the Liver transplants performed in our Center between February 24th and April 17th, 2020 with Liver transplants performed in the same period in 2019. Results In 2020, 21 patients underwent Liver transplantation from deceased donors, exactly as the year before, without statistically significant difference. All patients survived in both groups, and the rate of early graft dysfunction was 24% in 2020 and 33% in 2019. In 2020 Median MELD was higher (17vs 13). We were able to perform 3 multiorgan transplants and one acute liver failure. Nobody died on waiting list. The performance of our Center, despite the maxi-emergency situation, was steady and this was the result of a tremendous team working within the hospital and in our Region. Conclusions Team working allowed our Center to maintain its activity level, taking care of patients before and after Liver transplantation. Sharing our experience, we hope to be helpful to other Centers that are facing the pandemic and, if another pandemic comes, to be more prepared to deal with it.

Keywords: emergency; liver transplantation; covid emergency; region

Journal Title: Clinics and Research in Hepatology and Gastroenterology
Year Published: 2020

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