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Relationships Between Perinatal Interventions, Maternal-Infant Microbiomes, and Neonatal Outcomes.

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The human microbiome acquires its vastness and diversity over a relatively short time period during development. Much is unknown, however, about the precise prenatal versus postnatal timing or its sources… Click to show full abstract

The human microbiome acquires its vastness and diversity over a relatively short time period during development. Much is unknown, however, about the precise prenatal versus postnatal timing or its sources and determinants. Given early evidence of a role for influences during pregnancy and early neonatal and infant life on the microbiome and subsequent metabolic health, research investigating the development and shaping of the microbiome in the fetus and neonate is an important arena for study. This article reviews the relevant available literature and future questions on what shapes the microbiome during early development and mechanisms for doing so.

Keywords: perinatal interventions; interventions maternal; maternal infant; microbiomes neonatal; relationships perinatal; infant microbiomes

Journal Title: Clinics in perinatology
Year Published: 2018

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