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Emerging evidence suggests that changes to cellular metabolism can regulate epigenetic modifications to alter gene expression. Recently in Nature, Wu et al. show that the metabolic regulator AMPK can phosphorylate and… Click to show full abstract
Emerging evidence suggests that changes to cellular metabolism can regulate epigenetic modifications to alter gene expression. Recently in Nature, Wu et al. show that the metabolic regulator AMPK can phosphorylate and thus stabilize the epigenetic modifying enzyme TET2, defining a novel signaling link between metabolism and the epigenome.
Keywords:
metabolism;
tet2;
regulates epigenome;
phosphorylation tet2;
epigenome phosphorylation;
ampk regulates
Journal Title: Cell metabolism
Year Published: 2018
Link to full text (if available)
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Journal Title: Cell metabolism
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!