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Although confirmed as the primary lipophilic antioxidant molecule endogenously produced by cells, the non-mitochondrial pool of CoQ10's functional role is still well debated. Recently, both Bersuker et al. (2019) and Doll… Click to show full abstract
Although confirmed as the primary lipophilic antioxidant molecule endogenously produced by cells, the non-mitochondrial pool of CoQ10's functional role is still well debated. Recently, both Bersuker et al. (2019) and Doll et al. (2019) have identified FSP1 as a novel CoQ10 plasma membrane oxidoreductase, protecting cells from glutathione-independent ferroptosis.
Keywords:
non mitochondrial;
role non;
antioxidant role;
role;
mitochondrial coq10
Journal Title: Cell metabolism
Year Published: 2020
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Journal Title: Cell metabolism
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!