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Glycolysis supports effector T cell function but is detrimental to the immunosuppressive activity of regulatory T cells. In a recent issue of Nature, two papers address a role for glucose and lactate… Click to show full abstract
Glycolysis supports effector T cell function but is detrimental to the immunosuppressive activity of regulatory T cells. In a recent issue of Nature, two papers address a role for glucose and lactate availability within the tumor microenvironment for the balance of pro- and anti-tumoral effects of T cells and the efficacy of neoadjuvant cancer immunotherapy.
Keywords:
sugar dieting;
dieting tumor;
immunotherapy breaches;
breaches low;
tumor treg;
low sugar
Journal Title: Cell metabolism
Year Published: 2021
Link to full text (if available)
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Journal Title: Cell metabolism
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!