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A significant role of permeability on blood flow for hybrid nanofluid through bifurcated stenosed artery: Drug delivery application

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OBJECTIVE The prime objective of concerned article is to discuss the permeability impacts on blood flow by considering hybrid nanofluid through bifurcated stenosed artery. DESIGN/APPROACH The human body circulatory framework… Click to show full abstract

OBJECTIVE The prime objective of concerned article is to discuss the permeability impacts on blood flow by considering hybrid nanofluid through bifurcated stenosed artery. DESIGN/APPROACH The human body circulatory framework involves the arrangement of veins that fuse the bifurcation on parent, at apex and on regions of daughter artery with nanoparticles is viewed. Blood streaming is recognized as Newtonian along vessel segment. The walls of the stenosed bifurcated artery is considered to be permeable as well as compliant. Copper and its oxide as used as drug to minimize the stress and the lesions of the atherosclerotic artery. FINDINGS The theoretical investigation is carried out by invoking the experimental values of hybrid nanoparticles into the structured equations. Moreover, impacts of hemodynamics are also make sense of to inspect the progression of blood for atherosclerotic vein. Daughter and parent artery comparison is described through parabolic graph of velocity. Graphical illustration is utilized to present the theoretical results of this drug delivery model. Metallic nanoparticles justify their use in drug delivery. CONCLUSIONS The flow of blood is viewed as not quite the same as pressure between segments of atherosclerotic and non-atherosclerotic course. Bifurcation angle minimize the stress for daughter artery whereas trend is opposite for parent daughter. The change in compliant wall parameter reduces the circulating bolus size for parent daughter whereas for daughter artery the change in bolus shape is observed.

Keywords: drug delivery; daughter; blood; artery

Journal Title: Computer methods and programs in biomedicine
Year Published: 2020

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