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Multifocal myoclonus as a presentation of levetiracetam toxicity

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Highlights • Levetiracetam (LEV) is a widely used antiseizure medication, but LEV toxicity is not commonly reported.• We report a patient with chronic kidney disease who developed multifocal myoclonus after… Click to show full abstract

Highlights • Levetiracetam (LEV) is a widely used antiseizure medication, but LEV toxicity is not commonly reported.• We report a patient with chronic kidney disease who developed multifocal myoclonus after treatment with LEV.• The findings suggest the possibility of an inverted U-shaped dose–response of the anti-myoclonic effect of LEV.

Keywords: levetiracetam toxicity; myoclonus presentation; toxicity; presentation levetiracetam; multifocal myoclonus

Journal Title: Clinical Neurophysiology Practice
Year Published: 2021

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