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Highlights • Demyelination and increased axonal branching reduce the safety factor for impulse transmission.• Axonal hyperpolarization induced by voluntary contraction result in conduction block, and thereby fatigue in CIDP/SBMA patients.•… Click to show full abstract
Highlights • Demyelination and increased axonal branching reduce the safety factor for impulse transmission.• Axonal hyperpolarization induced by voluntary contraction result in conduction block, and thereby fatigue in CIDP/SBMA patients.• Activity-dependent conduction block causes peripheral fatigue in neuromuscular diseases.
Keywords:
conduction;
conduction block;
dependent conduction;
activity dependent
Journal Title: Clinical Neurophysiology Practice
Year Published: 2022
Link to full text (if available)
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Journal Title: Clinical Neurophysiology Practice
Year Published: 2022
Link to full text (if available)
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recommendations!