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Human pluripotent stem cells (hPSCs) hold great promise for modeling and recapitulation of human biological processes. Coupled with the advent of genome engineering tools, specifically the CRISPR–Cas9 systems, hPSCs have… Click to show full abstract
Human pluripotent stem cells (hPSCs) hold great promise for modeling and recapitulation of human biological processes. Coupled with the advent of genome engineering tools, specifically the CRISPR–Cas9 systems, hPSCs have opened a multitude of possibilities in modeling human biology and creating novel cellular therapies. Here, we review the fundamentals of both technologies, and the wide-ranging present and future applications of genome engineering in hPSCs.
Keywords:
engineering;
human pluripotent;
pluripotent stem;
stem cells;
genome engineering
Journal Title: Current opinion in chemical engineering
Year Published: 2017
Link to full text (if available)
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Journal Title: Current opinion in chemical engineering
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!