LAUSR

The longerterm secondary stability of an uncemented implant depends primarily on the quality and extent of bone in-growth or on-growth at the bone-implant interface. Investigations are warranted to predict the influences of implant macro-textures on bone on-growth pattern. Mechanoregulatory tissue differentiation algorithms can predict such patterns effectively. There is, however, a dearth of volumetric in silico study to assess the influence of macro-textures on bone growth. The present study investigated the influence of macro-textural grooves/ribs on changes in tissue formation at the bone-implant interface by carrying out a 3D finite element (FE) analysis. Three distinct macro-textures, loosely based on commercially viable hip stem models, were comparatively assessed for varying levels of interfacial micromotion. The study predicted elevated fibrogenesis and chondrogenesis, followed by a suppressed osteogenesis for higher levels of micromotion (60 μm and 100 μm), resulting in weak bone-implant interface strength. However, small judicious modifications in implant surface texture may enhance bone growth to a considerable extent. The numerical scheme can further be used as a template for more rigorous parametric and multi-scale studies.