Abstract In this work, a green composite from poly(3-hydroxybutyrate), or P(3HB), grafted with 2-amino-ethyl methacrylate, hydroxylated resin and silica nanoparticles was developed. The goal was to determine if the new… Click to show full abstract
Abstract In this work, a green composite from poly(3-hydroxybutyrate), or P(3HB), grafted with 2-amino-ethyl methacrylate, hydroxylated resin and silica nanoparticles was developed. The goal was to determine if the new poly(urethane-urea) composite can work as an appropriate substrate for biological applications. The mechanism for the polyurea step-growth polymerization was proposed. The scaffolds showed an average porosity and degree of swelling of 55% and 7%, respectively, as well as a reinforced mechanical strength compared to that of P(3HB). This material effectively supported the growth of the mammalian HEK293 cell line, as demonstrated by epifluorescence and confocal microscopy.
               
Click one of the above tabs to view related content.