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Highlights • Neuro-immune crosstalk occurs in distinct anatomical niches in the intestine.• Neuro-immune cell niches maintain gut homeostasis and modulate inflammation.• Neuron-macrophage crosstalk in the muscularis is crucial for neuronal… Click to show full abstract
Highlights • Neuro-immune crosstalk occurs in distinct anatomical niches in the intestine.• Neuro-immune cell niches maintain gut homeostasis and modulate inflammation.• Neuron-macrophage crosstalk in the muscularis is crucial for neuronal survival and peristalsis.• Mast cell mediators activate and sensitize nerve terminals, leading to aberrant pain perception.• Neurons modulate ILC function during infection and inflammation.
Keywords:
interactions focus;
macrophages mast;
intestinal neuro;
neuro immune;
focus macrophages;
immune interactions
Journal Title: Current Opinion in Neurobiology
Year Published: 2020
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Journal Title: Current Opinion in Neurobiology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!