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Sleep is an ancient and fundamental animal behavior. Sleep deprivation builds up sleep need to trigger recovery sleep, a homeostatic control crucial to maintain cognitive performance. Between several suggestions to… Click to show full abstract
Sleep is an ancient and fundamental animal behavior. Sleep deprivation builds up sleep need to trigger recovery sleep, a homeostatic control crucial to maintain cognitive performance. Between several suggestions to explain the indispensable nature of sleep, restoration of synapse plasticity is a prominent one, though causal relations here remained scarce. In this review, we will discuss recent advances reporting a mutual functional interplay between sleep deprivation-associated synaptic changes and sleep homeostasis.
Journal Title: Current Opinion in Neurobiology
Year Published: 2021
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