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OBJECTIVE To estimate the rate of requiring more than one 300-mcg Rh D immune globulin dose for fetomaternal hemorrhage (FMH) at the time of second-trimester dilation and evacuation (D+E). MATERIALS… Click to show full abstract
OBJECTIVE To estimate the rate of requiring more than one 300-mcg Rh D immune globulin dose for fetomaternal hemorrhage (FMH) at the time of second-trimester dilation and evacuation (D+E). MATERIALS AND METHODS We performed a retrospective cohort analysis of patients at greater than 20 weeks' gestation who underwent D+E, had Rh D-negative blood type, and received FMH quantification testing. RESULTS Of 25 eligible patients, 24 had negative quantification of FMH; one had positive quantification that did not meet the clinical threshold for additional dosing. CONCLUSIONS The absolute risk of requiring additional Rh D immune globulin after D+E for pregnancies greater than 20 weeks' gestation was 0%.
Journal Title: Contraception
Year Published: 2022
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