LAUSR

The locomotor network is a neural circuit capable of generating quite varied and complex patterns of motor activity. While neurotransmission and neuromodulation play a major role in fine-tuning motor function, neuron’s firing properties driven by a palette of intrinsic ionic conductances and pump currents, play an equally important role. This review highlights the papers published over the past few years studying ionic conductances in spinal circuits governing locomotion. I discuss how this ensemble of currents underpins the operation of the locomotor network and summarize progress towards identifying the channels that mediate the ionic conductances.