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The single-stranded Hepatitis C Virus (HCV) genome adopts a set of elaborate RNA structures that are involved in every stage of the viral lifecycle. Recent advances in chemical probing, sequencing,… Click to show full abstract
The single-stranded Hepatitis C Virus (HCV) genome adopts a set of elaborate RNA structures that are involved in every stage of the viral lifecycle. Recent advances in chemical probing, sequencing, and structural biology have facilitated analysis of RNA folding on a genome-wide scale, revealing novel structures and networks of interactions. These studies have underscored the active role played by RNA in every function of HCV and they open the door to new types of RNA-targeted therapeutics.
Keywords:
rna structures;
rna;
functional rna;
hepatitis virus
Journal Title: Current opinion in virology
Year Published: 2017
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Journal Title: Current opinion in virology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!