LAUSR

BACKGROUND Nutritional status is an important factor affecting prognosis of cardiovascular diseases. METHODS We compared major cardiovascular and cerebrovascular events (MACCE) between the malnutrition (Geriatric Nutritional Risk Index; GNRI <92) and non-malnutrition (GNRI ≥92) groups in 500 stable coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI) and evaluated coronary calcification by intravascular ultrasound. RESULTS Incidences of all-cause death and MACCE differed between the malnutrition and non-malnutrition groups (22% vs. 5%, p<0.001 and 24% vs. 6%, p<0.001). In multivariate Cox proportional hazards regression, malnutrition significantly correlated with all-cause death (p=0.006) and MACCE (p=0.010). The proportion of moderate/severe calcification differed between the malnutrition (64%) and non-malnutrition groups (33%, p<0.001). Multivariate logistic analysis identified age (p<0.001), malnutrition (p=0.048), and hemodialysis (p<0.001) as significantly related to moderate/severe calcification. CONCLUSIONS Malnutrition was an independent risk factor for all-cause death and MACCE in CAD patients after PCI and was associated with moderately/severely calcified lesions.