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Optical activity of lysozyme in solution at 532 nm via signal-reversing cavity ring-down polarimetry

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Abstract An improved optical cavity-based polarimetry method is employed to measure the optical activity of lysozyme in water solution, in the concentration range of 0–2 mg/ml. We employ a signal reversing… Click to show full abstract

Abstract An improved optical cavity-based polarimetry method is employed to measure the optical activity of lysozyme in water solution, in the concentration range of 0–2 mg/ml. We employ a signal reversing technique, which gives the absolute optical rotation, without needing to remove the sample for a null measurement. We report an absolute sensitivity limit on the order of 0.1 mdeg, corresponding to a detection limit of

Keywords: activity lysozyme; cavity; solution; optical activity; signal reversing

Journal Title: Chemical Physics Letters
Year Published: 2020

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