LAUSR

Abstract In this work, we firstly developed a new method for the synthesis of hierarchical mesoporous hollow Ce-MOF nanosphere templated by diblock copolymer. The hierarchical hollow mesoporous Ce-MOF nanosphere as the oxidase mimic shows highly catalytic chromogenic activity toward 3,3,5,5-tetramethylbenzidine (TMB) without the presence of H2O2, and it can be used as a substitute for peroxidase mimics and H2O2 system in the colorimetric reaction. Herein, we provide a new highly sensitive and selective colorimetric method for the detection of Ascorbic acid (AA). At the optimal pH (3.5), temperature (the room temperature), time (5 min) and TMB concentration (280 μM), the limit of detection (LOD) was 0.03 µM, the range of the detection was 8 to 56 µM.