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Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas

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Highlights • It is the largest series to report on 1618 1p19q co-deleted gliomas.• 51% of grade II get resection alone whereas 86% of grade III get adjuvant therapy.• In… Click to show full abstract

Highlights • It is the largest series to report on 1618 1p19q co-deleted gliomas.• 51% of grade II get resection alone whereas 86% of grade III get adjuvant therapy.• In a propensity score matched cohort, grade was significant for survival.• Hazard for death for grade III 1p19q co-deleted gliomas was about 3.6 times higher.• Oligodendroglioma histology was associated with a lower likelihood of death.

Keywords: grade; deleted gliomas; 1p19q deleted; grade iii; differences patterns

Journal Title: Clinical and Translational Radiation Oncology
Year Published: 2019

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