Highlights • Subcortical grey matter is susceptible to dose-dependent volume loss after RT.• Hippocampal age increases 1 year after radiotherapy, by a median of 11 years.• We may need to… Click to show full abstract
Highlights • Subcortical grey matter is susceptible to dose-dependent volume loss after RT.• Hippocampal age increases 1 year after radiotherapy, by a median of 11 years.• We may need to reconsider current sparing strategies in RT for brain tumours.• Future studies should examine the impact of deep GM volume loss on cognition.
               
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