Autophagosome biogenesis and the origins of its isolation membrane have been a long-standing unresolved question, with the endoplasmic reticulum and its membrane contact sites with other organelles remaining the prime… Click to show full abstract
Autophagosome biogenesis and the origins of its isolation membrane have been a long-standing unresolved question, with the endoplasmic reticulum and its membrane contact sites with other organelles remaining the prime suspect. This concept has now been reinforced by recent advances uncovering roles of several ER membrane proteins in autophagosome formation.
               
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