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Orbitofrontal Cortex: A ‘Non-rewarding’ New Treatment Target in Depression?

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Self-perpetuating activity in lateral orbitofrontal regions has been theorized to sustain the negative thoughts and emotions of depression. A new study demonstrates that disrupting such activity may yield rapid improvements… Click to show full abstract

Self-perpetuating activity in lateral orbitofrontal regions has been theorized to sustain the negative thoughts and emotions of depression. A new study demonstrates that disrupting such activity may yield rapid improvements in mood state, pointing the way to novel treatment strategies.

Keywords: treatment; rewarding new; orbitofrontal cortex; cortex non; new treatment; non rewarding

Journal Title: Current Biology
Year Published: 2019

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