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Genetic Variation: Harmful Recessive Mutations Have Unexpected Effects on Variation

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New data are causing the standard model for the effect of selection on linked neutral variation in low recombination regions, combining the effects of background selection and selective sweeps, to… Click to show full abstract

New data are causing the standard model for the effect of selection on linked neutral variation in low recombination regions, combining the effects of background selection and selective sweeps, to be refined to include harmful recessive mutations creating associative overdominance.

Keywords: variation; mutations unexpected; recessive mutations; harmful recessive; genetic variation; variation harmful

Journal Title: Current Biology
Year Published: 2020

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