The mechanism of chromosome biorientation during mitotic spindle assembly remains a century-old mystery. In contrast to the stochastic models that have dominated the field for decades, a new study now… Click to show full abstract
The mechanism of chromosome biorientation during mitotic spindle assembly remains a century-old mystery. In contrast to the stochastic models that have dominated the field for decades, a new study now proposes that chromosome biorientation is instead deterministic and driven by microtubule self-organization at kinetochores.
Keywords:
determined random;
search capture;
random search;
mitosis kinetochores;
biology;
kinetochores determined
Journal Title: Current Biology
Year Published: 2022
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Journal Title: Current Biology
Year Published: 2022
Link to full text (if available)
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recommendations!