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The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?

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Our laboratories have determined that the Drosophila cytokine, Growth-blocking peptide (GBP), mediates its biological effects through the Mthl10 G-protein coupled receptor. In this Cytokine Stimulus, we discuss the functional plasticity… Click to show full abstract

Our laboratories have determined that the Drosophila cytokine, Growth-blocking peptide (GBP), mediates its biological effects through the Mthl10 G-protein coupled receptor. In this Cytokine Stimulus, we discuss the functional plasticity of the GBP/Mthl10 axis, and we propose that conserved components of this regulatory network may be relevant to human health.

Keywords: gbp model; gbp; drosophila cytokine; cytokine gbp; illuminates yin; model illuminates

Journal Title: Cytokine
Year Published: 2018

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