Highlights • Cross-platform comparisons were conducted across five leading immunoassay platforms.• Plasma and serum were obtained from healthy controls and clinical populations.• Analytic parameters included sensitivity, precision, and performance correlation.•… Click to show full abstract
Highlights • Cross-platform comparisons were conducted across five leading immunoassay platforms.• Plasma and serum were obtained from healthy controls and clinical populations.• Analytic parameters included sensitivity, precision, and performance correlation.• Platform performance was highly variable, particularly for low-abundant cytokines.• Findings highlight certain immunoassays should be prioritized in future research.
               
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