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Dyslexia risk gene relates to representation of sound in the auditory brainstem

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Highlights • Previous studies associate poor reading with unstable speech-evoked brainstem responses.• DCDC2 and KIAA0319 risk alleles form a strong genetic link with developmental dyslexia.• Genetic burden with KIAA0319 risk… Click to show full abstract

Highlights • Previous studies associate poor reading with unstable speech-evoked brainstem responses.• DCDC2 and KIAA0319 risk alleles form a strong genetic link with developmental dyslexia.• Genetic burden with KIAA0319 risk is related to unstable speech-evoked brainstem responses.• Genetic burden with DCDC2 risk is related to intact speech-evoked brainstem responses.• Revealed brain-gene relationships may inform the multifactorial pathophysiology of dyslexia.

Keywords: speech evoked; risk; evoked brainstem; dyslexia; brainstem; gene

Journal Title: Developmental Cognitive Neuroscience
Year Published: 2017

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