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A Tale of Division and Polarization in the Mammalian Embryo.

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The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues… Click to show full abstract

The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.

Keywords: tale division; polarization; mammalian embryo; division polarization; cell; polarization mammalian

Journal Title: Developmental cell
Year Published: 2017

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