Immature β cells secrete insulin at a lower glucose threshold compared to mature β cells. In this issue of Developmental Cell, Huang et al. (2018) show that the increase in glucose… Click to show full abstract
Immature β cells secrete insulin at a lower glucose threshold compared to mature β cells. In this issue of Developmental Cell, Huang et al. (2018) show that the increase in glucose threshold during β cell maturation is achieved through balance between the Ca2+-sensitive synaptotagmin 7 and the Ca2+-insensitive synaptotagmin 4.
               
Click one of the above tabs to view related content.