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miRISC Composition Determines Target Fates in Time and Space.

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MicroRNA-mediated gene silencing can occur by either target mRNA degradation or translational repression. In this issue of Developmental Cell, Dallaire et al. (2018) show in C. elegans that tissue-specific composition of… Click to show full abstract

MicroRNA-mediated gene silencing can occur by either target mRNA degradation or translational repression. In this issue of Developmental Cell, Dallaire et al. (2018) show in C. elegans that tissue-specific composition of the silencing complex, miRISC, plays a major role in determining the fate of target mRNAs.

Keywords: mirisc; determines target; mirisc composition; target fates; composition; composition determines

Journal Title: Developmental cell
Year Published: 2018

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