MicroRNA-mediated gene silencing can occur by either target mRNA degradation or translational repression. In this issue of Developmental Cell, Dallaire et al. (2018) show in C. elegans that tissue-specific composition of… Click to show full abstract
MicroRNA-mediated gene silencing can occur by either target mRNA degradation or translational repression. In this issue of Developmental Cell, Dallaire et al. (2018) show in C. elegans that tissue-specific composition of the silencing complex, miRISC, plays a major role in determining the fate of target mRNAs.
               
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