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In this issue of Developmental Cell, Chew et al. (2019) show that the pioneer factor DUX4 is misexpressed in tumors, where it suppresses anti-tumor immune activity. Their findings provide a new… Click to show full abstract
In this issue of Developmental Cell, Chew et al. (2019) show that the pioneer factor DUX4 is misexpressed in tumors, where it suppresses anti-tumor immune activity. Their findings provide a new mechanism for immune evasion in cancer and highlight the pathogenic effects of re-expressing an embryonic program in adult cells.
Keywords:
bad unexpected;
roles dux4;
good bad;
dux4 health;
unexpected roles;
health disease
Journal Title: Developmental cell
Year Published: 2019
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Journal Title: Developmental cell
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!