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Prominin-2 Suppresses Ferroptosis Sensitivity.

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Ferroptosis causes clinically relevant amounts of necrosis during the course of heart attacks and acute kidney injury. However, ferroptosis is still a very young research field. In this issue of… Click to show full abstract

Ferroptosis causes clinically relevant amounts of necrosis during the course of heart attacks and acute kidney injury. However, ferroptosis is still a very young research field. In this issue of Developmental Cell, Brown et al. describe the pentaspan membrane glycoprotein prominin-2 as a novel endogenous ferroptosis inhibitor.

Keywords: prominin; ferroptosis; ferroptosis sensitivity; prominin suppresses; suppresses ferroptosis

Journal Title: Developmental cell
Year Published: 2019

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