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A Window into Your Gut: Biologically Inspired Engineering of Mini-gut Tubes In Vitro.

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Recently in Nature, using biologically inspired design principles to recapitulate native crypt-villi topography and luminal flow, Nikolaev et al. engineered an intestinal organotypic culture system that is capable of long-term epithelial… Click to show full abstract

Recently in Nature, using biologically inspired design principles to recapitulate native crypt-villi topography and luminal flow, Nikolaev et al. engineered an intestinal organotypic culture system that is capable of long-term epithelial homeostasis. Mini-gut tubes were used in month-long studies of parasite-host interactions and completely regenerated following injury.

Keywords: gut; window gut; biologically inspired; mini gut; gut tubes

Journal Title: Developmental cell
Year Published: 2020

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