Understanding how arteries develop is critical to design repair strategies for coronary artery disease and treatment of arteriovenous malformations. Luo et al. report in Nature that NOTCH drives coronary artery formation… Click to show full abstract
Understanding how arteries develop is critical to design repair strategies for coronary artery disease and treatment of arteriovenous malformations. Luo et al. report in Nature that NOTCH drives coronary artery formation by suppressing MYC, a transcription factor involved in cell cycle progression and cell metabolism.
               
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