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CDK4: Linking cell size to cell cycle control.

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A size checkpoint active during cell proliferation ensures that cells reach a certain target size before transitioning into S phase. In this issue of Developmental Cell, Tan et al. identify a… Click to show full abstract

A size checkpoint active during cell proliferation ensures that cells reach a certain target size before transitioning into S phase. In this issue of Developmental Cell, Tan et al. identify a distinct function of cyclin-dependent kinase 4 (CDK4) in determining the target cell size for cell cycle progression.

Keywords: cdk4; cell cycle; size; size cell; cell size; cell

Journal Title: Developmental cell
Year Published: 2021

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